PEC Zwolle 3 - 3 FC Utrecht

FC Porto 1 - 2 Sporting Clube de Braga

FC Schalke 04 2 - 0 Borussia Mönchengladbach

Fulham FC 1 - 0 Middlesbrough FC

CD Leganés 0 - 3 Getafe CF

Sporting Clube de Portugal 0 - 2 Sport Lisboa e Benfica

Levante UD - Deportivo Alavés

Queens Park Rangers FC - Leeds United AFC

Watford FC - Tottenham Hotspur FC

SS Lazio - UC Sampdoria

TSG 1899 Hoffenheim - Eintracht Frankfurt

FC Augsburg - BV Borussia 09 Dortmund

TSV Fortuna 95 Düsseldorf - SV Werder Bremen

1. FSV Mainz 05 - SC Freiburg

1. FC Köln - VfL Wolfsburg

Preston North End FC - Charlton Athletic FC

Real Madrid CF - Sevilla FC

Huddersfield Town AFC - Brentford FC

Bristol City FC - Barnsley FC

Millwall FC - Reading FC

Swansea City AFC - Wigan Athletic FC

Arsenal FC - Sheffield United FC

Southampton FC - Wolverhampton Wanderers FC

Norwich City FC - AFC Bournemouth

Birmingham City FC - Cardiff City FC

Derby County FC - Hull City AFC

Brighton & Hove Albion FC - Aston Villa FC

Manchester City FC - Crystal Palace FC

West Ham United FC - Everton FC

Sheffield Wednesday FC - Blackburn Rovers FC

Vitória SC - CD Santa Clara

CD Aves - Portimonense SC

US Sassuolo Calcio - Torino FC

CA Osasuna - Real Valladolid CF

Newcastle United FC - Chelsea FC

RB Leipzig - 1. FC Union Berlin

Fortuna Sittard - SBV Vitesse

CD Tondela - Moreirense FC

FC Twente '65 - FC Groningen

Feyenoord Rotterdam - SC Heerenveen

AZ - Willem II Tilburg

SSC Napoli - ACF Fiorentina

SD Eibar - Club Atlético de Madrid

Os Belenenses Futebol - Vitória FC